Internal Med Medical News about Inhalation Pulmonary Disease, Chronic Obstructive Metered Dose Inhalers

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The ADMIT series - Issues in Inhalation Therapy. 4) How to choose inhaler devices for the treatment of COPD
Primary Care Respiratory Journal, 11/05/09

Although efficacy and safety are the primary factors determining the choice of an inhaler device, randomised controlled trials (RCTs) directly comparing the efficacy and safety of different inhalers in COPD patients are scarce. Systematic reviews on this subject failed to find significant differences between devices for any of the clinical outcomes studied. When selecting a device for the delivery of inhaled drugs in ‘real life’ patients with COPD, other factors should be considered. These include availability and affordability of the inhaled drugs and inhaler devices, the uniformity of inhaler devices when several drugs are to be inhaled, the ability of patients to handle correctly the selected device – in particular taking into account the advanced age of the average COPD patient, and finally the patient’s preference. The prescribing clinician’s task is to provide comprehensive instructions for correct handling of the device and to review regularly the patient’s inhalation technique.

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Peak inspiratory flow through the Genuair inhaler in patients with moderate or severe COPD
Respiratory Medicine, 11/13/09 Relevance Score: 97%

Long-term therapy in COPD: any evidence of adverse effect on bone
International Journal of COPD, 10/01/09 Relevance Score: 95%

Patient preferences for inhaler devices in chronic obstructive pulmonary disease: experience with Respimat Soft Mist Inhaler
International Journal of COPD, 10/15/09 Relevance Score: 93%

Sequential comparison of tiotropium to high-dose ipratropium in patients with chronic obstructive pulmonary disease in a practice setting
International Journal of COPD, 10/15/09 Relevance Score: 93%

Iloprost Improves Gas Exchange and Exercise Tolerance in Patients with Pulmonary Hypertension and Chronic Obstructive Pulmonary Disease
Respiration, 10/14/09 Relevance Score: 93%