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See Latest ArticlesSinus aspergilloma in rheumatoid arthritis before or during tumor necrosis factor-alpha antagonist therapy
Arthritis Research & Therapy, 11/10/09
Leboime A et al. – Otorhinolaryngological symptoms must be evaluated before starting or switching TNF-alpha antagonists. Routine computed tomography of the sinuses before starting or switching TNF-alpha antagonists may deserve consideration.
Methods- Retrospective descriptive study of symptomatic cases of sinus aspergilloma in patients with RA followed in three French university hospitals
- Systematic literature review performed
- 550 RA patients treated with TNF-alpha antagonists, 6 (1.1%) had symptomatic maxillary aspergilloma diagnosed by computed tomography before or during TNF-alpha antagonist therapy
- None had chronic neutropenia
- Aspergilloma treatment was with surgery only in all 6 patients
- 20 reports of Aspergillus infection in patients with chronic inflammatory joint diseases (including 10 with RA)
- Only 5/20 patients were treated with TNF-alpha antagonists (invasive lung aspergillosis, n=3; intracranial aspergillosis, n=1; and sphenoidal sinusitis, n=1)
Today in Clinical Pharmacology...keeping you current
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Effects of metformin with or without supplementation with folate on homocysteine levels and vascular endothelium of women with polycystic ovary syndrome
Diabetes Care, 11/25/09
Low-Density Lipoprotein Cholesterol Reduction and Goal Achievement With Ezetimibe/Simvastatin Versus Atorvastatin or Rosuvastatin in Patients With Diabetes, Metabolic Syndrome, or Neither Disease, Stratified By National Cholesterol Education Program Risk Category
Metabolic Syndrome and Related Disorders, 11/25/09
Intravenous Drug Administration During Out-of-Hospital Cardiac Arrest: A Randomized Trial
JAMA, 11/25/09
Today in Hematology/Oncology...keeping you current
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High-Resolution Flow Cytometry: a Suitable Tool for Monitoring Aneuploid Prostate Cancer Cells after TMZ and TMZ-BioShuttle Treatment
International Journal of Medical Sciences , 11/25/09
Comparative study of control selection in a national population -based case-control study: Estimating risk of smoking on cancer deaths in Chinese men
International Journal of Medical Sciences , 11/25/09
Prospective studies of dietary alpha-linolenic acid intake and prostate cancer risk: a meta-analysis
Cancer Causes and Control, 11/25/09
Today in Rheumatology...keeping you current
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Effect of alendronate on bone metabolic indices and bone mineral density in patients treated with high-dose glucocorticoid: A prospective study
Osteoporosis International, 11/25/09
Treatment of osteoporosis: Recognizing and managing cutaneous adverse reactions and drug-induced hypersensitivity
Osteoporosis International, 11/25/09
Prevalent vertebral deformity independently increases incident vertebral fracture risk in middle-aged and elderly Japanese women: The Japanese Population-based Osteoporosis (JPOS) Cohort Study
Osteoporosis International, 11/25/09
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