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Autosomal Dominant Polycystic Kidney Disease: New Treatment Options and How to Test Their Efficacy
Kidney and Blood Pressure Research, 11/06/09

Wuthrich RP et al. – In order to prevent the latter, one needs to act on the former, i.e. current belief by experts in the field is that retardation of cyst growth will ultimately improve the loss of glomerular filtration rate, and cyst volume is an ideal surrogate parameter for outcome in early ADPKD. The present review will discuss the utility and the techniques for kidney and cyst volume measurements to assess disease progression in ADPKD, and summarizes ongoing clinical trials testing novel therapeutic options.

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Cystic Changes of Breast in a Family With Autosomal Dominant Polycystic Kidney Disease
Iranian Journal of Kidney Diseases, 10/13/09 Relevance Score: 68%

Loss of Tsc1, but not Pten, in renal tubular cells causes polycystic kidney disease by activating mTORC1
Human Molecular Genetics, 11/03/09 Relevance Score: 67%

Autosomal Dominant Polycystic Kidney Disease: Current and Emerging Treatments
Kidney, 10/30/09 Relevance Score: 67%

Psoas abscess in hemodialysis patients
International Urology and Nephrology, 10/06/09 Relevance Score: 66%

The Role of the Mammalian Target Of Rapamycin (mTOR) in Renal Disease
Journal of the American Society of Nephrology, 11/04/09 Relevance Score: 65%