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Czernichow S et al. – Clinical trials show that the expected weight loss is 3 to 4 Kg compared with placebo. In addition, orlistat should improve blood sugar and lipid levels and reduce blood pressure. Sibutramine increases HDL cholesterol, decreases triglycerides but increases the blood pressure and heart rate. A trial is underway to study the impact of these adverse effects in subjects at high cardiovascular risk. Therefore, the field for the development of new drugs for treating overweight and obesity remains wide open.

Today in Atherosclerosis/Lipids...keeping you current

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Postgraduate Medicine, 11/24/09

Colesevelam HCl Improves Fasting Plasma Glucose and Lipid Levels in Patients with Prediabetes
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Today in Clinical Pharmacology...keeping you current

Inhibition of specific adenylyl cyclase isoforms by lithium and carbamazepine, but not valproate, may be related to their antidepressant effect
Bipolar Disorders, 11/24/09

Antipsychotic Prescribing Practices Following Withdrawal of Concomitant Carbamazepine
Journal of Psychiatric Practice, 11/24/09

Impact of pharmaceutical dosage form on stability and dissolution of roxithromycin
Central European Journal of Medicine, 11/24/09

Today in Vascular Medicine...keeping you current

How Stiff Are Your Arteries? An Emerging Vital Sign for Determining Cardiovascular Disease Risk
The Journal for Nurse Practitioners , 11/24/09

Connective Tissue Reflex Massage for Type 2 Diabetic Patients with Peripheral Arterial Disease: Randomized Controlled Trial
Evidence-based Complementary and Alternative Medicine , 11/24/09

YKL-40 - an emerging biomarker in cardiovascular disease and diabetes
Cardiovascular Diabetology, 11/24/09


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