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Diagnostic transitions in mild cognitive impairment subtypes
International Psychogeriatrics, 11/04/09

Forlenza OV et al. – The clinical diagnosis of MCI and its subtypes yields groups of patients with heterogeneous patterns of transitions between one given cognitive state to another. The presence of more severe and widespread cognitive deficits, as indicated by the group of multiple–domain amnestic MCI may be a better predictor of AD than single–domain amnestic or non–amnestic deficits. These higher–risk individuals could probably be the best candidates for the development of preventive strategies and early treatment for the disease.

Exclusive Author Commentary
Orestes Vicente Forlenza, 11/04/09

We understand that biomarker technologies (e.g., amyloid imaging with PET, or the quantification of AD-like molecules in the CSF) will add important insights into the clinical and neuropsychological heterogeneity of MCI. But it is reasonable to assume that these resources are highly specialized, and may not be available in most clinical settings. The identification of subtle changes in the cognition and the functional status, compatible with the expected pattern of transitions in the MCI-AD continuum, may add accuracy to the diagnosis of Alzheimer’s disease at pre-dementia stages.

Update on Pelvic floor dysfunction
OBG Management, 10/06/09 Relevance Score: 68%

The cognitive effects of chemotherapy in post-menopausal breast cancer patients: a controlled longitudinal study
Breast Cancer Research and Treatment, 11/12/09 Relevance Score: 67%

An open trial with cognitive behavioral therapy for blood- and injection phobia in pregnant women-a group intervention program
Archives of Women's Mental Health, 11/03/09 Relevance Score: 67%

Perceptions of group music therapy among elderly nursing home residents in Taiwan
Complementary Therapies in Medicine, 10/28/09 Relevance Score: 67%

For SAD Sufferers, Cognitive Behavior Better Than Light Therapy At Preventing Recurrence, Study Suggests
ScienceDaily, 10/19/09 Relevance Score: 67%