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Glycation of a food allergen by the Maillard reaction enhances its T-cell immunogenicity: Role of macrophage scavenger receptor class A type I and II
Journal of Allergy and Clinical Immunology, 10/30/09
Ilchmann A et al. – SR–AI/II targets AGE–OVA to the MHC class II loading pathway in mDCs, leading to an enhanced CD4+ T–cell activation. The Maillard reaction might thus play an important role in the T–cell immunogenicity of food allergens.
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