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Epidemiologic Studies of Styrene and Cancer: A Review of the Literature
Journal of Occupational and Environmental Medicine, 10/28/09

Boffetta P et al. – The authors found no consistent increased risk of any cancer among workers exposed to styrene. A study of reinforced plastic workers reported an association between average estimated styrene exposure and non–Hodgkin lymphoma but no trend with increasing duration of exposure. Other studies of styrene exposure and NHL found no increased risk. In two US studies of reinforced plastic workers, esophageal cancer mortality was increased, but these findings were generated in a background of multiple comparisons. Results for other cancers were unremarkable. The available epidemiologic evidence does not support a causal relationship between styrene exposure and any type of human cancer.