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Morita E et al. – Analysis using purified wheat proteins revealed that approximately 80% of the patients with WDEIA have IgE reacting to omega–5 gliadin and the remaining of the patients to high molecular weight glutenin (HMW–glutenin). Simultaneous measurement of specific IgE to omega–5 gliadin and HMW–glutenin was found to be highly useful in diagnosing WDEIA compared with the routine diagnostic system for wheat.

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