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See Latest ArticlesHuman Siglec-10 can bind to vascular adhesion protein-1 (VAP-1) and generate enzymatic products
Blood, 11/10/09
Kivi E et al. – The interaction between Siglec–10 and VAP–1 led to increased hydrogen peroxide production indicating that Siglec–10 serves as a substrate for VAP–1. Thus, Siglec–10 –– VAP–1 interaction seems to mediate lymphocyte adhesion to endothelium and has the potential to modify the inflammatory microenvironment via the enzymatic end products.
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