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CIS is a surrogate marker of genetic instability and field carcinogenesis in the urothelial mucosa
Urologic Oncology: Seminars and Original Investigations, 10/27/09
Palmeira C et al. – This study points out that CIS is a marker of genetic instability of the urothelium mucosa. The CIS surrounding morphologically normal urothelium showed a high frequency of abnormal DNA content, with high percentage of clear aneuploid cells (high 5cER), p53 mutated protein expression, and a proliferative status underlying a field carcinogenesis. These alterations in normal mucosa were not found when CIS was not present.
Today in Basic Science/Genetics...keeping you current
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Advances in fibromyalgia treatment: understanding endogenous pain modulation
International Journal of Clinical Rheumatology, 11/09/09
How triggers trigger acute migraine attacks: A hypothesis
Medical Hypotheses, 11/23/09
Functional activation of proline-rich tyrosine kinase2 (PYK2) in peripheral blood mononuclear cells from patients with systemic lupus erythematosus
BMC Musculoskeletal Disorders, 11/18/09
Today in Hematology/Oncology...keeping you current
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Approach to Thrombocytopenia in Older Adults
Geriatrics & Aging, 11/10/09
Update on oral lichen planus
Expert Review of Dermatology, 10/14/09
Revised American Thyroid Association Management Guidelines for Patients with Thyroid Nodules and Differentiated Thyroid Cancer
Thyroid, 10/30/09
Today in Nephrology/Urology...keeping you current
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Systematic Review: Sodium Bicarbonate Treatment Regimens for the Prevention of Contrast-Induced Nephropathy
Annals of Internal Medicine, 11/03/09
Mycophenolate mofetil and intravenous cyclophosphamide are similar as induction therapy for class V lupus nephritis
Kidney International, 11/05/09
Managing diabetes in hemodialysis patients: Observations and recommendations
Cleveland Clinic Journal of Medicine, 11/04/09
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