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See Latest ArticlesA case of linear immunoglobulin A bullous dermatosis in a patient exposed to sun and an analgesic
Clinical Therapeutics, 10/29/09
Pellicano R et al. – A 45–year–old woman developed LABD lesions on sun–exposed skin after 3 days of sunbathing and consumption of a medication for headache containing propyphenazone, butalbital, and caffeine. The lesions spread to unexposed skin and, by day 5, the patient had vesicles and bullae on the palms and soles, face, trunk, and extremities. LABD was diagnosed with direct and indirect immunofluorescence microscopy and Western blot analysis. Treatment was successful with prednisone, started at a dosage of 1 mg/kg/d, for 5 months. Lesions located on sunexposed areas, the absence of relapse for 5 years despite continuing sun exposure against medical advice, and subsequent avoidance of the suspected medication suggest that the bullous flare may have been due to the concomitant action of 2 triggers. That the analgesic had a role in this cutaneous manifestation is possible according to the Naranjo algorithm for adverse drug reactions.
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Today in Clinical Pharmacology...keeping you current
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Effects of metformin with or without supplementation with folate on homocysteine levels and vascular endothelium of women with polycystic ovary syndrome
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Low-Density Lipoprotein Cholesterol Reduction and Goal Achievement With Ezetimibe/Simvastatin Versus Atorvastatin or Rosuvastatin in Patients With Diabetes, Metabolic Syndrome, or Neither Disease, Stratified By National Cholesterol Education Program Risk Category
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Today in Dermatology...keeping you current
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Familial atypical cold urticaria: Description of a new hereditary disease
Journal of Allergy and Clinical Immunology, 11/25/09
Schnitzlers syndrome with prominent neutrophil infiltration misdiagnosed as Sweets syndrome: a typical example of urticarial neutrophilic dermatosis
Clinical and Experimental Dermatology, 11/25/09
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Today in Pain Management...keeping you current
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How Humans Integrate the Prospects of Pain and Reward during Choice
Journal of Neuroscience, 11/25/09
Sacral Nerve Stimulation as a Treatment Modality for Intractable Neuropathic Testicular Pain
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Ultrasound-Guided Cryoablation of Genitofemoral Nerve for Chronic Inguinal Pain
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