Internal Med Medical News about Pulmonary Disease, Chronic Obstructive Spirometry

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Severity Staging of Chronic Obstructive Pulmonary Disease: Differences in Pre- and Post-Bronchodilator Spirometry
Yonsei Medical Journal, 10/23/09

Lin S–H et al. – For the entire study population, the FEV1 increased by 11.8 ± 12.5% of baseline after BDT and 41.1% and 27.1% of subjects were classified as responders using the ATS and ERS criteria, respectively. Based on pre–BDT spirometry, 55, 85, 58, and 9 patients were classified as Stage I–IV COPD, respectively. Sixty–seven (32.4%) patients changed severity staging after BDT, including 20.0%, 28.2%, 44.8%, and 66.7% of pre–BDT patients Stages I through IV, respectively. More ATS or ERS BDT–responders had a change in severity staging than non–responders. These data suggest that the severity staging of COPD using pre–BDT spirometry might lead to significant differences as compared to staging, based on post–BDT spirometry, as recommended by the current GOLD guidelines.

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