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Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1
Nature, 10/23/09
Barbie DA et al. – The observations indicate that TBK1 and NF–kB signalling are essential in KRAS mutant tumours, and establish a general approach for the rational identification of co–dependent pathways in cancer.
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Today in Basic Science/Genetics...keeping you current
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Polymorphonuclear neutrophils and cancer: Intense and sustained neutrophilia as a treatment against solid tumors
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The emerging role of cardiovascular risk factor-induced mitochondrial dysfunction in atherogenesis
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