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The interaction of TIGIT with PVR and PVRL2 inhibits human NK cell cytotoxicity
Proceedings of the National Academy of Sciences of the United States of America, 10/22/09
Stanietsky N et al. – The authors show that TIGIT counter inhibits the NK–mediated killing of tumor cells and protects normal cells from NK–mediated cytoxicity thus providing an “alternative self” mechanism for MHC class I inhibition.
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Distribution and Cardiovascular Risk Correlates of Plasma Soluble Intercellular Adhesion Molecule-1 Levels in Asymptomatic Young Adults from a Biracial Community: The Bogalusa Heart Study
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