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Is Bone's Response to Mechanical Signals Dominated by Muscle Forces
Medicine and Science in Sports and Exercise, 10/26/09
Robling AG – Load–induced osteogenesis requires that mechanical signals come packaged with particular characteristics, all of which can be generated from either gravitational or muscle forces. Neither of these two sources have been demonstrated empirically to be the source of bone's adaptive response, but a convincing body of data suggests that muscle contractions are present, significant, and capable of accounting for most of the adaptive responses.
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