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See Latest ArticlesPharmacological Inhibition of Transforming Growth Factor [beta] Signaling Decreases Infection and Prevents Heart Damage in Acute Chagas' Disease
Antimicrobial Agents and Chemotherapy, 11/05/09
Waghabi MC et al. – Inhibition of TGF–[beta] signaling in vivo appears to potently decrease T. cruzi infection and to prevent heart damage in a preclinical mouse model. This suggests that this class of molecules may represent a new therapeutic agent for acute and chronic Chagas' disease that warrants further clinical exploration.
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