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See Latest ArticlesEthnic differences in pediatric systemic lupus erythematosus
Journal of Rheumatology, 10/20/09
Hiraki LT et al. – Non-Caucasian ethnicity is associated with increased pSLE disease prevalence. Non-Caucasian pSLE patients were significantly younger and more likely to have nephritis. However, disease activity and damage were strongly associated with major organ disease independent of the patient’s ethnicity.
Methods- Ethnic demographic profiles of inception cohort of 265 patients with pSLE followed at Sick Kids Hospital in Toronto determined and compared to Metropolitan Toronto at-risk population
- Patients categorized into ethnic subsets based on self-designated ethnic origins
- Disease characteristics including major organ involvement, disease activity, and damage measures longitudinally determined and compared among ethnic groups
- Ethnicity data available on 259/265 pSLE patients (99.6%); the majority were non-Caucasian (60%) compared to Metropolitan Toronto at-risk population (40%)
- Non-Caucasian patients younger at diagnosis than Caucasian patients, Black patients being youngest at diagnosis
- Renal disease significantly more common in non-Caucasian than Caucasian pSLE patients
- Trend toward increased prevalence of CNS disease in Black patients compared to Asian patients
- No difference in gender ratio, SLE Disease Activity Index, or damage scores between ethnic groups
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Atherogenic lipoprotein phenotype and LDL size and subclasses in drug-naïve patients with early rheumatoid arthritis
Atherosclerosis, 12/08/09
Total cholesterol and triglycerides are associated with the development of new bone marrow lesions in asymptomatic middle-aged women - a prospective cohort study
Arthritis Research & Therapy, 12/08/09
Silica exposure among male current smokers is associated with a high risk of developing ACPA positive rheumatoid arthritis
Annals of Rheumatic Diseases, 12/08/09
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