Internal Med Medical News about Men Pain Insulin-Like Growth Factor I

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Perturbed Insulin-like Growth Factor-1 (IGF-1) and IGF Binding Protein-3 Are Not Associated with Chronic Widespread Pain in Men: Results from the European Male Ageing Study
Journal of Rheumatology, 10/16/09

McBeth J et al. – Overall chronic widespread pain (CWP) was not associated with perturbations in IGF–1 and IGFBP–3 concentrations. Hypofunctioning of the axis was noted among subjects who were obese and this was not specific to CWP. These data suggest that IGF–1 is unlikely to be etiologically important in relation to CWP, although the relationship with growth hormone remains to be elucidated.

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