Internal Med

Your Article Summary

See Latest Articles

Vitamin D and its role in skeletal muscle
Current Opinion in Clinical Nutrition & Metabolic Care, 10/21/09

Ceglia L – Molecular mechanisms of vitamin D action in muscle tissue include genomic and nongenomic effects via a receptor present in muscle cells. Knockout mouse models of the vitamin D receptor provide insight into understanding the direct effects of vitamin D on muscle tissue. Vitamin D status is positively associated with physical performance and inversely associated with risk of falling. Vitamin D supplementation has been shown to improve tests of muscle performance, reduce falls, and possibly impact on muscle fiber composition and morphology in vitamin D deficient older adults. Further studies are needed to fully characterize the underlying mechanisms of vitamin D action in human muscle tissue, to understand how these actions translate into changes in muscle cell morphology and improvements in physical performance, and to define the 25–hydroxyvitamin D level at which to achieve these beneficial effects in muscle.

Today in Orthopedic/Physical Med...keeping you current

Receive free subspecialty "5-minute updates" via email

Effect of biomagnetic therapy versus physiotherapy for treatment of knee osteoarthritis: A randomized controlled trial
Journal of Rehabilitation Medicine, 11/20/09

Osteoarthritis: A review of treatment options
Geriatrics, 10/21/09

Bisphosphonate therapy: When not to monitor BMD
The Journal of Family Practice, 11/02/09

See All of Orthopedic/Physical Med