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Benington S et al. – In fully mechanically ventilated patients, dynamic measurements of heart–lung interaction such as stroke volume variation are superior to static measures of preload in assessing whether a patient is volume–responsive (i.e. will increase stroke volume in response to a fluid challenge). For patients who are not fully mechanically ventilated, pulse contour analysis allows real–time assessment of increases in cardiac output in response to passive leg–raising.

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