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See Latest ArticlesModulation of Neuropathic Pain by a Glial-Derived Factor
Pain Medicine, 10/14/09
Adler JE et al. – Intrathecal application of GDNF stimulates expression of somatostatin, a neuropeptide with potential analgesic properties. Moreover, stimulation of dorsal root sensory neurons with GDNF in vitro increases cell content of somatostatin, which, in turn, leads to increased secretion in response to depolarizing stimuli. The authors suggest that GDNF exerts its anti–allodynic effect via somatostatinergic mechanisms. These observations suggest new approaches for treating nerve injury that may prove useful in preventing delayed complications that contribute to long–term debility.
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Today in Basic Science/Genetics...keeping you current
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Multilocus methylation analysis in a large cohort of 11p15-related foetal growth disorders (Russell Silver and Beckwith Wiedemann syndromes) reveals simultaneous loss of methylation at paternal and maternal imprinted loci
Human Molecular Genetics, 11/25/09
Adenosine deamination in human transcripts generates novel microRNA binding sites
Human Molecular Genetics, 11/25/09
Skeletal dysplasias due to filamin A mutations result from a gain-of-function mechanism distinct from allelic neurological disorders
Human Molecular Genetics, 11/25/09
Today in Neurology...keeping you current
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Accumulation of gene polymorphisms related to plaque disruption and thrombosis is associated with cerebral infarction in subjects with type 2 diabetes
Diabetes Care, 11/25/09
Effect of cilnidipine vs losartan on cerebral blood flow in hypertensive patients with a history of ischemic stroke: a randomized controlled trial
Acta Neurologica Scandinavica, 11/25/09
Long-term Neurologic Outcomes After Traumatic Brain Injury
Journal of Head Trauma Rehabilitation, 11/25/09
Today in Pain Management...keeping you current
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How Humans Integrate the Prospects of Pain and Reward during Choice
Journal of Neuroscience, 11/25/09
Sacral Nerve Stimulation as a Treatment Modality for Intractable Neuropathic Testicular Pain
Pain Physician, 11/25/09
Ultrasound-Guided Cryoablation of Genitofemoral Nerve for Chronic Inguinal Pain
Pain Physician, 11/25/09
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