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Insulin-like factor 3 as a marker of testicular function in obese men
Clinical Endocrinology, 10/16/09

Foresta C et al. – This study showed for the first time that INSL3 levels decrease with obesity, probably as a result of a primary dysfunction of the Leydig cells. INSL3 is a reliable marker of Leydig cell general impairment, whereas T mainly reflects the steroidogenic activity of these cells.

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