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Central and peripheral airway sites of nitric oxide gas exchange in COPD
Chest, 10/14/09
Gelb AF et al. – In COPD, there was normal NO gas exchange in both large and small airways/alveoli and only large airway NO flux was suppressed with F250/S50 but not F100/S50 despite varying extent of emphysema. Peripheral NO must be corrected for axial NO backdiffusion to avoid spurious conclusions.
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