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El–Shazly AE et al. – Idiopathic selective CD4+ lower baseline cell count and an increase in CD8+ cells is an unusual immune defect. Whether this is a true variant of idiopathic CD4+ T lymphocytopenia (ICL) or a sequelae to recurrent infections is not clear...Taken collectively, these preliminary results may indicate a novel role for IL–7 in enhancing the CCR3 expression and function in patients of this syndrome and highlights the novel role of IL–10 in inducing a significant increase in CD4+–expressing lymphocytes from the patient when compared to controls.


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