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Risk of dying from prostate cancer in men randomized to screening
Cancer, 10/13/09

Bergdahl AG et al. – Nonattendees in prostate cancer screening constitute a high-risk group for both death from prostate cancer and death from other causes comparable to that described in other cancer screening programs. Cancer 2009. © 2009 American Cancer Society.

Methods

10,000 men randomly assigned to active PSA-screening every second year
Prostate cancer mortality attributed to whether men were attendees in screening program (attending at least once) or nonattendees

Results

39 men died from prostate cancer during the first 13 years
Overall (34% vs 13 %) and cancer-specific mortality (0.8% vs 0.3 %) found to be significantly higher among nonattendees compared with attendees
Majority of deaths (12 of 18) among screening attendees in men diagnosed at first screening
6 deaths (including 3 interval cases) noted among men complying with biennial screening program

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