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See Latest ArticlesCT60 and +49 polymorphisms of CTLA 4 are associated with ANCA-positive small vessel vasculitis
Rheumatology, 10/12/09
Kamesh L et al. – Results of this study provide further evidence that CTLA-4, a susceptibility locus for a number of common autoimmune diseases, may also be involved in the development of ANCA-associated SVV
Methods- 222 white Caucasians of UK origin with SVV
- 670 ethnically matched controls
- CTLA-4 CT60 (exon 4), +49 (exon 1) and –318 (promoter region) genotypes determined by PCR and restriction fragment length polymorphism (RFLP)
- CTLA-4 exon 1 (+49) and 4 (CT60) polymorphisms associated with SVV
- Both disease-susceptible and disease-protective haplotypes identified in cohort
- Frequencies similar in subtypes of WG and microscopic polyangiitis
Today in Rheumatology...keeping you current
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Effect of alendronate on bone metabolic indices and bone mineral density in patients treated with high-dose glucocorticoid: A prospective study
Osteoporosis International, 11/25/09
Treatment of osteoporosis: Recognizing and managing cutaneous adverse reactions and drug-induced hypersensitivity
Osteoporosis International, 11/25/09
Prevalent vertebral deformity independently increases incident vertebral fracture risk in middle-aged and elderly Japanese women: The Japanese Population-based Osteoporosis (JPOS) Cohort Study
Osteoporosis International, 11/25/09
Today in Vascular Medicine...keeping you current
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The prognostic impact of general and abdominal obesity in peripheral arterial disease
International Journal of Obesity, 11/25/09
Prospective analysis of risk factors and distribution of venous thromboembolism in the population-based Malmo Thrombophilia Study (MATS)
Thrombosis Research, 11/25/09
Effect of cilnidipine vs losartan on cerebral blood flow in hypertensive patients with a history of ischemic stroke: a randomized controlled trial
Acta Neurologica Scandinavica, 11/25/09
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