Internal Med Medical News about AIDS-Associated Nephropathy

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Interventions for HIV-associated nephropathy
Cochrane Reviews, 10/20/09

Yahaya I et al. – HIV–associated nephropathy (HIVAN) is a kidney disease common among HIV positive patients, especially patients of African origin. The condition rapidly deteriorates if left untreated. Various treatment options exist, but the benefit of each is unknown. These include: antiretrovirals, steroids, angiotensin–converting enzyme inhibitors (ACEI) and cyclosporin. The aim of this review was to determine the benefits and harms of each treatment option. No completed randomised control trials (RCT) of any interventions for HIVAN were found and so the effects of the treatment options could not be evaluated. However, the results of observational studies identified showed that steroids and ACEI were beneficial in improving the kidney functions of patients. The authors await the results of three ongoing studies, however more RCTs are needed.

Nephropathy in Type 1 diabetes is associated with increased circulating activated platelets and platelet hyperreactivity
Platelets, 10/30/09 Relevance Score: 46%

Renal Cell Carcinoma in Association With IgA Nephropathy in the Elderly
The American Journal of the Medical Sciences, 11/13/09 Relevance Score: 45%

Pro12Ala polymorphism in the PPARG gene contributes to the development of diabetic nephropathy in Chinese type 2 diabetes
Diabetes Care, 10/28/09 Relevance Score: 45%

DNase1 activity in systemic lupus erythematosus patients with and without nephropathy
Rheumatology International, 10/26/09 Relevance Score: 45%

Scoring system for renal pathology in Fabry disease: report of the International Study Group of Fabry Nephropathy (ISGFN)
Nephrology Dialysis Transplantation, 10/16/09 Relevance Score: 45%