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Prevalence of Antinuclear Antibodies in 3 Groups of Healthy Individuals: Blood Donors, Hospital Personnel, and Relatives of Patients With Autoimmune Diseases
Journal of Clinical Rheumatology (JCR), 10/16/09
Marin GG et al. – ANA should generally not be tested without clinical indication. Positive ANA finding in the absence of physical signs and symptoms has limited diagnostic utility and should always be interpreted by a rheumatologist, in the context of clinical symptoms and results of laboratory tests for specific autoantibodies. Populations such as doctors and relatives of patients with autoimmune disease tend to presents increased ANA titers.
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