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Synthetic carbohydrate-based anticancer vaccines: the Memorial Sloan-Kettering experience
Expert Review of Vaccines, 10/08/09
Zhu J et al. – The carbohydrate–based anticancer vaccine program has evolved through a number of stages: monomeric vaccines, monomeric clustered vaccines, unimolecular multi–antigenic vaccines and dual–acting vaccines. This account will focus on the recently developed unimolecular multi–antigenic constructs and potential dual–acting constructs, which contain clusters of both carbohydrate and peptide epitopes.
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