Internal Med Medical News about Antiviral Agents Chemoprevention Influenza, Human

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Systematic Review: Safety and Efficacy of Extended-Duration Antiviral Chemoprophylaxis Against Pandemic and Seasonal Influenza
Annals of Internal Medicine, 10/06/09

Khazeni N et al. – This review of 7 trials assessing the efficacy and safety of extended–duration (>4 weeks) treatment with oseltamivir and zanamivir suggests that the drugs prevent symptomatic but not asymptomatic seasonal influenza. Extended–duration zanamivir and oseltamivir chemoprophylaxis seems to be highly efficacious for preventing symptomatic influenza among immunocompetent white and Japanese adults. Extended–duration oseltamivir is associated with increased nausea and vomiting. Safety and efficacy in several subpopulations that might receive extended–duration influenza chemoprophylaxis are unknown.

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Antiviral Agents for Influenza: Molecular Targets, Concerns of Resistance, and New Treatment Options
Current Drug Targets, 10/23/09 Relevance Score: 89%

The next ten stories on antiviral drug discovery (part E): Advents, Advances, and Adventures
Medicinal Research Reviews, 10/21/09 Relevance Score: 88%

Using Complementary and Alternative Medicines to Target the Host Response during Severe Influenza
Evidence-based Complementary and Alternative Medicine, 10/05/09 Relevance Score: 80%

Relationship between equipment and infrastructure for pandemic influenza and performance in an avian flu drill
Emergency Medicine Journal, 10/23/09 Relevance Score: 79%

Effectiveness and Cost-Effectiveness of Expanded Antiviral Prophylaxis and Adjuvanted Vaccination Strategies for an Influenza A (H5N1) Pandemic
Annals of Internal Medicine, 10/13/09 Relevance Score: 79%