Internal Med Medical News about Churg-Strauss syndrome

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Churg-Strauss syndrome successfully treated with rituximab
Rheumatology International, 10/15/09

Donvik KK et al. – Churg–Strauss syndrome (CSS) is characterized by small–vessel vasculitis, extravascular granulomatous inflammation, and massive eosinophilia in tissues and blood, and is often accompanied by a history of preclinical asthma and/or allergic rhinitis lasting several years before the syndrome develops its full clinical picture. The authors describe two patients resistant to conventional therapy who were treated with rituximab and experienced a rapid and substantial decrease in disease activity and asthmatic symptoms and an increase in physical capacity.

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