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The Efficacy and Duration of Intra-articular Corticosteroid Injection for Knee Osteoarthritis: A Systematic Review of Level I Studies
Journal of the American Academy of Orthopedic Surgeons, 10/01/09
Hepper CT et al. – Following an electronic search of multiple databases and a review of reference lists from various articles, the authors found 6 trials in 5 papers that compared corticosteroid versus placebo and four papers that compared different corticosteroids. Results of corticosteroid compared with placebo showed both a statistically and clinically significant reduction in pain at 1 week, with an average difference between groups of 22%. 2 of 4 trials showed triamcinolone to be more effective in pain reduction than other corticosteroids. The authors concluded that intra–articular corticosteroids reduce knee pain for at least 1 week and that intra–articular corticosteroid injection is a short–term treatment of a chronic problem.
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Today in Clinical Pharmacology...keeping you current
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Treatment with alpha-lipoic acid reduces asymmetric dimethylarginine in patients with type 2 diabetes mellitus
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Calcium phosphate cement to prevent collapse in avascular necrosis of the femoral head
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The efficacy of calcitriol therapy in the management of bone loss and fractures: A qualitative review
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Methylnaltrexone: the evidence for its use in the management of opioid-induced constipation
Core Evidence, 12/11/09
Predictive factors of adherence to frequency and duration components in home exercise programs for neck and low back pain: an observational study
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Pain perception during esophageal warming due to radiofrequency catheter ablation in the left atrium
Journal of Interventional Cardiac Electrophysiology , 12/11/09
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Criterion Contamination of Depression Scales in Patients with Rheumatoid Arthritis: The Need for Interpretation of Patient Questionnaires (as All Clinical Measures) in the Context of All Information About the Patient
Rheumatic Disease Clinics of North America, 12/11/09
The HAQ Compared with the MDHAQ: Keep It Simple, Stupid (KISS), with Feasibility and Clinical Value as Primary Criteria for Patient Questionnaires in Usual Clinical Care
Rheumatic Disease Clinics of North America, 12/11/09
A survey of European and Canadian rheumatologists regarding the treatment of patients with ankylosing spondylitis and extra-articular manifestations
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