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Psoriasis - as an autoimmune disease caused by molecular mimicry
Trends in Immunology, 09/30/09
Valdimarsson H et al. – The streptococcal association might reflect the concurrence of superantigen production promoting skin–homing of tonsil T cells, M–protein mimicking keratin determinants, and adjuvant effects of the peptidoglycan. Accordingly, improvement of psoriasis after tonsillectomy should be associated with fewer T cells that recognize keratin and streptococcal determinants.
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Today in Allergy/Immunology...keeping you current
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Today in Dermatology...keeping you current
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