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Systematic review of progesterone for the prevention of preterm birth in singleton pregnancies
Acta Obstetricia et Gynecologica Scandinavica, 09/28/09

Rode L et al. – In women with a singleton pregnancy and previous preterm delivery, progesterone reduces the rates of preterm delivery before 32 weeks, perinatal death, as well as respiratory distress syndrome and necrotizing enterocolitis in the newborn. Women with a short cervix or preterm labor may also benefit from progesterone, but further evidence is needed to support such a recommendation. Follow–up studies should focus on possible metabolic complications in the mother or the offspring.