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Elevated serum cytokines during human anaphylaxis: Identification of potential mediators of acute allergic reactions
Journal of Allergy and Clinical Immunology, 09/25/09
Stone SF et al. – This study confirms that the concentrations of a number of cytokines are elevated in blood during anaphylaxis in human beings and that some correlate with the presence of hypotension. Others were only marginally elevated within a concentration range that available assays do not reliably detect. During respiratory reactions, mediators may be largely confined to the airways so that blood concentrations do not reflect activity.
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