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See Latest ArticlesParaoxonase Variants Relate to 10-Year Risk in Coronary Artery Disease
JACC - Journal of the American College of Cardiology, 09/23/09
Regieli JJ et al. – PON–1 gene variants influence the 10–year risk of fatal complications from CAD in male patients, despite no effect on all–cause mortality. These long–term findings confirm functional data on PON–1 activity, emphasize the relevance of this pathway in vascular disease, and enforce its putative role as a target to modify and estimate cardiovascular risk.
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