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Charlson Comorbidity Index does not predict long-term mortality in elderly subjects with chronic heart failure
Age and Aging, 09/17/09
Testa G et al. – Charlson Comorbidity Index (CCI) does not predict long–term mortality in elderly subjects with CHF.
Methods- Long–term mortality after 12–year follow–up in 125 subjects with CHF and 1,143 subjects without CHF was studied.
- Comorbidity was evaluated using Charlson Comorbidity Index.
- In elderly subjects stratified for CCI (1–3 and >=4), mortality was higher in non–CHF subjects with CCI >=4 (52.4% versus 70%, P < 0.002) but not in those with CHF (75.9% versus 77.6%, P = 0.498, NS).
- Cox regression analysis on 12 years mortality indicated that both CCI and CHF were predictive of mortality.
- When Cox analysis was performed by selecting the presence and the absence of CHF, CCI was predictive of mortality in the absence but not in the presence of CHF.
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