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Trigonelline Is a Novel Phytoestrogen in Coffee Beans
The Journal of Nutrition, 08/27/09
Allred F et al. – Drinking coffee has been associated with the development of several endocrine–related cancers. The interpretation of these data has often been limited to the role that caffeine plays. Trigonelline (Trig), a niacin–related compound, is a natural constituent of coffee accounting for 1% dry matter in roasted beans...These data demonstrate that Trig even at low concentrations stimulates estrogen–dependent human breast cancer (MCF–7) cell growth and that this effect is mediated through estrogen receptor (ER), clearly identifying Trig as a novel phytoestrogen.
Today in Basic Science/Genetics...keeping you current
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Advances in fibromyalgia treatment: understanding endogenous pain modulation
International Journal of Clinical Rheumatology, 11/09/09
How triggers trigger acute migraine attacks: A hypothesis
Medical Hypotheses, 11/23/09
Functional activation of proline-rich tyrosine kinase2 (PYK2) in peripheral blood mononuclear cells from patients with systemic lupus erythematosus
BMC Musculoskeletal Disorders, 11/18/09
Today in Endocrinology...keeping you current
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Carbohydrate-restricted diets for obesity and related diseases: An update
Current Atherosclerosis Reports, 11/17/09
Systematic Review: Comparative Effectiveness and Harms of Combination Therapy and Monotherapy for Dyslipidemia
Annals of Internal Medicine, 11/03/09
Comparison of Simvastatin and Metformin in Treatment of Polycystic Ovary Syndrome: Prospective Randomized Trial
Journal of Clinical Endocrinology and Metabolism, 11/20/09
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Approach to Thrombocytopenia in Older Adults
Geriatrics & Aging, 11/10/09
Update on oral lichen planus
Expert Review of Dermatology, 10/14/09
Revised American Thyroid Association Management Guidelines for Patients with Thyroid Nodules and Differentiated Thyroid Cancer
Thyroid, 10/30/09
Today in Preventive Medicine...keeping you current
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Homocysteine lowering interventions for preventing cardiovascular events
Cochrane Reviews, 10/19/09
Antithrombotic medication for stroke prevention
Expert Review of Cardiovascular Therapy , 10/20/09
Omega-3 fatty acids and heart failure
Current Atherosclerosis Reports, 11/12/09
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