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Ulriksen LS et al. – Patients with IHD had significantly lower FMD than patients without IHD. During a mean follow–up of 4.2 years, 90 patients had an endpoint event, i.e. cardiovascular death, acute MI, unstable angina pectoris, PCI or CABG. In univariate analysis, FMD <3 % was associated with an increased hazard of the combined endpoint. In multivariate analysis, adjusted for age, gender, IHD and body mass index, no association between FMD and the combined endpoint was found. FMD is associated with IHD, but has no independent prognostic effect in patients with chest pain.

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