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See Latest ArticlesFactors associated with anemia in patients with cancer admitted to an intensive care unit
Journal of Critical Care, 07/29/09
Cardenas-Turanzas M et al. - Study reports that clinical factors are more influential than demographic factors in prevalence and incidence of anemia in the intensive care unit (ICU). Thus, protocols are needed to identify subgroups of patients with cancer who could benefit from novel management strategies.
Methods- An evaluation of the relative impact of clinical and demographic factors associated with the prevalence and incidence of anemia in critically ill cancer pts
- An electronic chart review for demographic and clinical data was performed
- Prevalence of anemia determined at admission
- Incidence determined if anemia developed during ICU stay
- Anemia was classified as mild, moderate, or severe
- Additive impact of clinical and demographic factors was evaluated by using a hierarchical linear regression model
- 4705 pts; prevalence and incidence of anemia were 68.0% and 46.6%, respectively
- In prevalent cases, it was found that the clinical covariates modified:
- Sequential organ failure assessment score
- Admission to the medical ICU
- Prior chemotherapy
- Diagnosis of hematologic cancer
- Length of hospital stay before ICU admission explained 18.7% of the variance in the model
- Demographic covariates (age, sex, and race) explained only an additional 0.6%
- The pattern was similar for incidence cases
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