Your Article Summary
See Latest ArticlesCochrane Musculoskeletal Group review: Acute gout
The Journal of Family Practice, 07/02/09
Winzenberg T et al. - Gout afflicts about 2% of men over age 30 and women over age 50 and its prevalence appears to be increasing. Options for treating acute gout include nonsteroidal anti-inflammatory drugs (NSAIDs), colchicine, and intra-articular and systemic corticosteroids. Choosing among them can be challenging, however, because the evidence that one or another of these options yields real benefit is of varying strength. Using NSAIDs can be problematic with increasing age, as comorbidities like gastrointestinal (GI) bleeding, renal failure, heart failure, and cardiovascular risk increase and anticoagulant therapy is more likely to be in use. That’s where the kind of systematic reviews Cochrane Musculoskeletal Group (CMSG) performs can be of real help.
- Test your skills with 2 cases
- All 22 participants who took colchicine developed diarrhea or vomiting within 24 hours of initiating therapy
- One RCT found that oral prednisolone 35 mg daily and naproxen 500 mg twice daily were clinically equivalent
- NSAIDs are a reasonable first option, provided there are no contraindications
Related Articles
Outcome Domains for Studies of Acute and Chronic Gout
Journal of Rheumatology, 10/20/09
Relevance Score: 69%
Progress in Measurement Instruments for Acute and Chronic Gout Studies
Journal of Rheumatology, 10/23/09
Relevance Score: 68%
The modern management of gout
Rheumatology, 10/08/09
Relevance Score: 66%
Acute chylous ascites mimicking acute appendicitis in a patient with pancreatitis
World Journal of Gastroenterology, 10/20/09
Relevance Score: 47%
Acute silent cerebral infarction in children with sickle cell anemia
Pediatric Blood & Cancer, 10/09/09
Relevance Score: 46%
Today in Clinical Pharmacology...keeping you current
Receive free subspecialty "5-minute updates" via email
Interferon-gamma (INF-gamma) release test can detect cutaneous adverse effects to statins
International Journal of Dermatology, 12/03/09
Amlodipine/Valsartan/Hydrochlorothiazide: Fixed-Dose Combination in Hypertension
American Journal of Cardiovascular Drugs, 12/03/09
Rosiglitazone May Assist With Glycemic Control on the ICU
Journal of Intensive Care Medicine, 12/03/09
Today in Rheumatology...keeping you current
Receive free subspecialty "5-minute updates" via email
Continuing Medical Education Challenges in Chronic Fatigue Syndrome
BMC Medical Education, 12/03/09
Telangiectases in scleroderma: A potential clinical marker of pulmonary arterial hypertension
Journal of Rheumatology, 12/03/09
Vitamin K2 supplementation does not influence bone loss in early menopausal women: A randomised double-blind placebo-controlled trial
Osteoporosis International, 12/03/09