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Alpha 4+ beta 7hiCD4+ memory T cells harbor most Th-17 cells and are preferentially infected during acute SIV infection
Mucosal Immunology, 07/02/09
Kader M et al. - Results show that resting memory alpha 4+ beta 7hiCD4+ T cells in the blood are preferentially infected and depleted during acute SIV infection, and the loss of these cells alters the balance between Th-17 and Th-1 responses, thereby contributing to disease pathogenesis.
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