Your Messages Inbox
Most Viewed Abstracts
1. Report Shows Shift in Starting Salaries for Physicians 2. Recommendations on the use of 18F-FDG PET in oncology 3. Gene expression signatures, clinicopathological features, and individualized therapy in breast cancer 4. AHA Guidelines on Cardiac CT for Assessing Coronary Artery Disease 5. Rapid correction of low vitamin D status in nursing home residents
Top Ten Searches
etanercept hypertension chf antiphospholipid fibrosis mrsa scid renal cell rickets counterpulsationYour Article Summary
See Latest ArticlesLack of specificity of the 6-minute walk test as an outcome measure for patients with systemic sclerosis
Journal of Rheumatology, 07/02/09
Schoindre Y et al. – Data demonstrate that the 6-min walking distance (6MWD) relates to broad factors in systemic sclerosis (SSc), raising the doubts about the specificity of this test in SSc and its relevance to monitoring therapy.
Methods- An evaluation of the relationships of 6MWD and organ damage in SSc
- 87 pts underwent 6MWT in addition to:
- conventional assessment of possible lung, heart, kidney, skin, and muscle involvement
- disease activity scoring, severity, and
- quality of life determination
- 30% pts had an abnormal 6MWT and the mean 6MWD was 461.8±103.0 m
- When considering 6MWT as a binary variable, normal or abnormal CRP was the only independent variable associated with abnormal 6MWT
- Considered as a continuous variable, the 6MWD was associated with:
- Measures of lung involvement and inflammation
- Activity and severity of disease, and
- Quality of life
- Nevertheless, calcinosis was the only independent factor associated in multivariate analyses with a trend for an association for CRP
Related Articles
Measures of Response in Clinical Trials of Systemic Sclerosis: The Combined Response Index for Systemic Sclerosis (CRISS) and Outcome Measures in Pulmonary Arterial Hypertension Related to Systemic Sclerosis (EPOSS)
Journal of Rheumatology, 10/15/09
Relevance Score: 72%
Necrotizing fasciitis in a patient with overlap syndrome of systemic sclerosis and systemic lupus erythematosus
Rheumatology International, 11/16/09
Relevance Score: 68%
Aerobic Exercise is Safe and Effective in Systemic Sclerosis
International Journal of Sports Medicine, 10/14/09
Relevance Score: 67%
High frequency ultrasound measurement of digital dermal thickness in systemic sclerosis
Annals of Rheumatic Diseases, 10/23/09
Relevance Score: 66%
Mechanisms of vascular damage in systemic sclerosis
Autoimmunity, 10/02/09
Relevance Score: 66%
Today in Radiology/Diagnostics...keeping you current
Receive free subspecialty "5-minute updates" via email
Association between oxidant/antioxidant markers and proteinuria in type 2 diabetes: results in 142 patients
Journal of Nephrology, 12/07/09
Perspectives of nuclear diagnostic imaging in diabetic cardiomyopathy
Nutrition, Metabolism & Cardiovascular Diseases, 12/07/09
Advanced Cardiovascular Sonographer: A Proposal of the American Society of Echocardiography Advanced Practice Sonographer Task Force
Journal of The American Society of Echocardiography, 12/07/09
Today in Rheumatology...keeping you current
Receive free subspecialty "5-minute updates" via email
Site of psoriasis (scalp or intergluteal/perianal), >=3 affected sites, and nail dystrophy predicted psoriatic arthritis in incident psoriasis
Evidence-Based Medicine, 12/07/09
Both weight-bearing and non-weight-bearing exercise improved function in patients with knee osteoarthritis
Evidence-Based Medicine, 12/07/09
MLN3897 plus methotrexate in patients with rheumatoid arthritis: Safety, efficacy, pharmacokinetics, and pharmacodynamics of an oral CCR1 antagonist in a phase IIa, double-blind, placebo-controlled, randomized, proof-of-concept study
Arthritis & Rheumatism, 12/07/09
Sponsor
Article Search
Sponsor
Sponsor