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Characterization of the allergic T-cell response to Pru p 3, the nonspecific lipid transfer protein in peach
Journal of Allergy and Clinical Immunology, 07/02/09
Schulten V et al. - The T-cell response to Pru p 3 is dominated by TH2 cells presumably primed in the gut. The identification of relevant T cell–activating regions provides a basis for engineering hypoallergenic variants of Pru p 3 with less IgE binding and retained T-cell stimulatory capacity for safe immunotherapy of peach allergy.
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