Internal Med Medical News about Rheumatoid arthritis

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Rheumatoid arthritis is linked to oral bacteria: Etiological association
Modern Rheumatology, 07/01/09

Ogrendik M – Review to evaluate the association between rheumatoid arthritis (RA) and periodontopathic bacteria. The presented evidence indicates that oral bacteria directly associate with etiopathogenesis of RA. Periodontal infections should be treated and prevented from becoming chronic.

Clinical studies have provided evidence for a significant association between the 2 disorders
High levels of oral anaerobic bacterial antibodies have been found in the serum and synovial fluid of RA pts
Porphyromonas gingivalis, Tannerella forsythensis, and Prevotella intermedia have been identified in RA synovial fluid
Ornidazole, levofloxacin, and clarithromycin are used in the treatment of infections caused by anaerobic bacteria
These antibiotics have been shown to be effective against RA

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Efficacy of roxithromycin in adult patients with rheumatoid arthritis who had not received disease-modifying antirheumatic drugs: A 3-month, randomized, double-blind, placebo-controlled trial
Clinical Therapeutics, 10/15/09 Relevance Score: 71%

Certolizumab Pegol: In Rheumatoid Arthritis
BioDrugs, 11/11/09 Relevance Score: 70%

Assistive technology for rheumatoid arthritis
Cochrane Reviews, 10/09/09 Relevance Score: 70%

Treatment of early RA with infliximab is beneficial
American Pharmacists Association, 11/06/09 Relevance Score: 69%

Abatacept for rheumatoid arthritis
Cochrane Reviews, 10/09/09 Relevance Score: 69%