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Fatty acids as metabolic mediators in innate immunity
European Journal of Clinical Investigation, 07/02/09
Kopp A et al. - Monocytic activation is differentially regulated by fatty acids and depends on triglyceride levels in T2D. The main finding of the present study shows that eicosapentaenoic acid inhibits the specific binding of LPS to TLR4/MD-2. Eicosapentaenoic acid represents a new anti-inflammatory LPS-antagonist.
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