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See Latest ArticlesDexamethasone and hypoxia upregulate CXCR4 expression in myeloma cells
Leukemia and Lymphoma, 07/02/09
Kim SW et al. - Incubation of cells under hypoxic conditions (1% O2) also induced upregulation of CXCR4 in the cytoplasm and on the cell surface and enhanced chemotaxis in response to stromal cell-derived factor-1 (SDF-1). Cell surface CXCR4 expression was more prominent in annexin V-positive apoptotic cells. Given the roles of the SDF-1/CXCR4 axis in the development and progression of myeloma, CXCR4-downregulating agents may enhance the antitumor effects of dexamethasone.
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Today in Clinical Pharmacology...keeping you current
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Resorption and elimination kinetics of benzoic acid during chemical necrectomy in deep burns
Scandinavian Journal of Clinical and Laboratory Investigation, 12/19/09
Hemodialysis in Hypotensive Heart Failure Using Midodrine
The American Journal of the Medical Sciences, 12/17/09
Today in Dermatology...keeping you current
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The Influence of Environmental Temperature on the Response of the Skin to Local Pressure: The Impact of Aging and Diabetes
Diabetes Technology & Therapeutics, 12/17/09
Smoking, sun exposure, number of nevi and previous neoplasias are risk factors for melanoma in older patients (60 years and over)
Journal of the European Academy of Dermatology and Venereology, 12/17/09
Low-dose methotrexate treatment for moderate-to-severe atopic dermatitis in adults
Journal of the European Academy of Dermatology and Venereology, 12/17/09
Today in Hematology/Oncology...keeping you current
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Ferric Carboxymaltose in Patients with Heart Failure and Iron Deficiency
New England Journal of Medicine, 12/17/09
Invasive front of colorectal cancer: Dynamic interface of pro-/anti-tumor factors
World Journal of Gastroenterology, 12/17/09
Neoadjuvant peptide receptor radionuclide therapy for an inoperable neuroendocrine pancreatic tumor
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