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See Latest ArticlesEpigenetic Regulation of Cytokine Gene Expression in T Lymphocytes
Yonsei Medical Journal, 07/02/09
Lee CG et al. - Recent studies have elucidated the important role of chromatin remodeling and epigenetic changes for proper regulation of gene expression of lineage-specific cytokines. These include DNA methylation and histone modifications in epigenomic reprogramming during T helper cell development and effector T cell functions. This review discusses the basic epigenetic mechanisms and the role of transcription factors for the differential cytokine gene regulation in the T helper lymphocyte subsets.
Today in Allergy/Immunology...keeping you current
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A genome-wide association study on African-ancestry populations for asthma
Journal of Allergy and Clinical Immunology, 11/25/09
Reassessing the role of hyaluronidase in yellow jacket venom allergy
Journal of Allergy and Clinical Immunology, 11/25/09
Familial atypical cold urticaria: Description of a new hereditary disease
Journal of Allergy and Clinical Immunology, 11/25/09
Today in Basic Science/Genetics...keeping you current
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Multilocus methylation analysis in a large cohort of 11p15-related foetal growth disorders (Russell Silver and Beckwith Wiedemann syndromes) reveals simultaneous loss of methylation at paternal and maternal imprinted loci
Human Molecular Genetics, 11/25/09
Adenosine deamination in human transcripts generates novel microRNA binding sites
Human Molecular Genetics, 11/25/09
Skeletal dysplasias due to filamin A mutations result from a gain-of-function mechanism distinct from allelic neurological disorders
Human Molecular Genetics, 11/25/09
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