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Promoter Methylation in the Genesis of Gastrointestinal Cancer
Yonsei Medical Journal, 07/02/09
Boland CR et al. - This paper reviews the types of genetic alterations that can be found in CRCs and hepatocellular carcinoma (HCC), and focuses upon the epigenetic alterations that result in promoter methylation and the CpG island methylator phenotype (CIMP). The challenge facing CRC research and clinical care at this time is to deal with the heterogeneity and complexity of these genetic and epigenetic alterations, and to use this information to direct rational prevention and treatment strategies.
Today in Basic Science/Genetics...keeping you current
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Multilocus methylation analysis in a large cohort of 11p15-related foetal growth disorders (Russell Silver and Beckwith Wiedemann syndromes) reveals simultaneous loss of methylation at paternal and maternal imprinted loci
Human Molecular Genetics, 11/25/09
Adenosine deamination in human transcripts generates novel microRNA binding sites
Human Molecular Genetics, 11/25/09
Skeletal dysplasias due to filamin A mutations result from a gain-of-function mechanism distinct from allelic neurological disorders
Human Molecular Genetics, 11/25/09
Today in Gastroenterology...keeping you current
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Clinical Features of Gastroduodenal Ulcer in Japanese Patients Taking Low-Dose Aspirin
Digestive Diseases and Sciences, 11/25/09
KRAS Mutational Status as a Predictor of Epidermal Growth Factor Receptor Inhibitor Efficacy in Colorectal Cancer
American Journal of Therapeutics, 11/25/09
Peg-Interferon in Acute and Chronic Hepatitis C: A Review
American Journal of Therapeutics, 11/25/09
Today in Hematology/Oncology...keeping you current
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High-Resolution Flow Cytometry: a Suitable Tool for Monitoring Aneuploid Prostate Cancer Cells after TMZ and TMZ-BioShuttle Treatment
International Journal of Medical Sciences , 11/25/09
Comparative study of control selection in a national population -based case-control study: Estimating risk of smoking on cancer deaths in Chinese men
International Journal of Medical Sciences , 11/25/09
Prospective studies of dietary alpha-linolenic acid intake and prostate cancer risk: a meta-analysis
Cancer Causes and Control, 11/25/09
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