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See Latest ArticlesEarly detection of coronary artery disease by 64-slice multidetector computed tomography in asymptomatic hypertensive high-risk patients
International Journal of Cardiology, 06/26/09
Gaudio C et al. – The 64-slice multidetector-row computed tomography (MDCT) is an excellent noninvasive technique for early identification of significant coronary stenoses in high-risk asymptomatic hypertensive pts and may provide unique information for screening this broad population.
Methods- Study of the value of MDCT vs invasive coronary angiography (ICA) for detecting presence and extent of coronary atherosclerotic plaques in a population of asymptomatic, hypertensive pts considered at high risk for cardiovascular events
- Assessment of 67 asymptomatic, hypertensive pts at high-risk (Euro Score >5%)
- Both MDCT and ICA for all pts (all had negative or nondiagnostic findings at exercise stress testing)
- In per-pt analysis, MDCT correctly identified 16/17 (94%) pts with significant coronary artery disease involving ≥1 vessel and 48/50 (96%) normal subjects
- In per-segment analysis, MDCT correctly detected 21/22 (95%) coronary segments with stenosis ≥50% and 856/868 (98%) normal segments, with high negative predictivity of normal scans (100%)
- Good concordance between MDCT and ICA; high Pearson correlation coefficient between coronary narrowings with the 2 techniques
- Mean coronary calcium score higher on ICA for 17 pts with vs 50 pts without significant coronary artery disease
- ROC curves identified 160 as best calcium volumetric score cut-off value able to identify ≥1 significant coronary stenosis with sensitivity 88% and specificity 85%
Today in Cardiology...keeping you current
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Acute Coronary Syndromes: Diagnosis and Management, Part I
Mayo Clinic Proceedings, 10/05/09
Acute medical management of the non-ST-segment elevation acute coronary syndromes (NSTE-ACS) in older patients
Archives of Gerontology and Geriatrics, 10/14/09
New Anticoagulants in Atrial Fibrillation
Seminars in Thrombosis and Hemostasis, 10/02/09
Today in Radiology/Diagnostics...keeping you current
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Allergic rhinitis with negative skin tests: Does it exist
Allergy and Asthma Proceedings, 10/13/09
Risk of dying from prostate cancer in men randomized to screening
Cancer, 10/13/09
Hemoglobin A1C and diabetes diagnosis: The Rancho Bernardo Study
Diabetes Care, 10/28/09
Today in Vascular Medicine...keeping you current
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Antithrombotic medication for stroke prevention
Expert Review of Cardiovascular Therapy , 10/20/09
A selective endothelin-receptor antagonist to reduce blood pressure in patients with treatment-resistant hypertension: a randomised, double-blind, placebo-controlled trial
The Lancet, 10/27/09
Effectiveness of Two-Year Clopidogrel + Aspirin in Abolishing the Risk of Very Late Thrombosis After Drug-Eluting Stent Implantation (from the TYCOON [Two-Year ClOpidOgrel Need] Study)
The American Journal of Cardiology, 11/05/09
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